Induction therapy in lung transplantation
نویسندگان
چکیده
منابع مشابه
Alemtuzumab induction therapy in solid organ transplantation
Alemtuzumab (Campath) is a monoclonal antibody that has a profound lymphocyte-depleting effect, targeting the CD52 antigen that is present on all lymphocytes. Alemtuzumab has been used for the treatment of chronic lymphocytic leukaemia and various autoimmune disorders, and has also shown potential as an induction agent in the prevention of rejection following solid organ transplantation. Alemtu...
متن کاملLong-term outcomes following alemtuzumab induction in lung transplantation.
OBJECTIVES Alemtuzumab is a commonly used induction agent for solid-organ transplantation. Its use in lung transplantation with reduced immunosuppressive regimens, however, has yet to be well characterized. METHODS From November 2006 to March 2008, 20 consecutive lung transplantation patients received alemtuzumab induction with a reduced maintenance immunosuppression regimen. Twenty consecuti...
متن کاملClinical experience with induction therapy in renal transplantation
INTRODUCTION Acute rejection (AR) is a major determinant of renal allograft survival. The incorporation of new immunosuppressive agents explains the improvement seen in the results of transplantation in recent years. OBJECTIVE To assess the optimal immunosuppression regimen according to the immunological risk of renal transplant patients. METHOD We performed a retrospective study of 977 con...
متن کاملImmunosuppressive therapy in lung transplantation: state of the art.
The coming of age of lung transplantation is accompanied by an immunosuppressive armamentarium that has been brought forward from other transplant indications. Widely employed on the basis of few small randomized studies, and mostly single-center experience or empirical expert knowledge, anti-rejection therapeutic strategies in pulmonary transplantation have hardly been rigorously evaluated in ...
متن کاملInduction Therapy: A Modern Review of Kidney Transplantation Agents
Kidney transplantation remains the most effective modality for the treatment of end-stage renal disease. The development of induction therapy has significantly reduced the incidence of acute rejection within the first six months following kidney transplantation. As a result, induction therapy is typically administered in the majority of kidney transplants. Moreover, early graft function has als...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2013
ISSN: 0934-0874
DOI: 10.1111/tri.12115